Endocrine Abstracts

Background and aims: Type 2 Diabetes Mellitus affects a growing number of people allover the world. It is associated with serious complications. Several studies have shown that it is possible to prevent and minimize type 2 diabetes complications if it is treated appropriately over time. In our Hospital there is, since 1998, an outpatient clinics of diabetes. This study aimed to determine the quality of care provided to diabetic patients in our institution.<p class="abstext...

Background and aims: Thyroid nodular disease (TND) is a common condition in the general population. Malignant nodules occur in 5% of patients with thyroid nodules. Fine-needle aspiration biopsy (FNAB) is considered to be the most reliable method of differentiating benign and malignant thyroid nodules. The purpose of this study was to assess the accuracy of FNABs performed in our Hospital.Methods: We retrospectively reviewed the medical records of patient...

Objective: To analyse the effects of bariatric surgery on the global coronary risk profile two years after the surgical procedure.Methods: A total of 32 class III obese patients, 6 men and 26 women, mean age 34.3±8.5 years, were included. Total Cholesterol (TC), HDL, triglycerides, Blood Pressure (BP), presence of diabetes and smoking were evaluated before and two years after bariatric surgery. The 10 year Framingham coronary heart disease risk scor...

Objective: The purpose of this study was to assess clinical outcomes of patients with toxic adenoma (TA) treated with Radioactive Iodine (RAIT) in a tertiary hospital over a period of 8 years. We also analysed the influence of age, gender, TSH at diagnosis and anti-thyroid drugs (ATD) previous to RAIT on the cure rate.Methods: Retrospective analysis of clinical records of all patients with TA submitted to RAIT between 2008 and 2015. The influence of demo...

Introduction: Thyroid hormones modulate the insulin sensitivity and glucose metabolism. The interrelation between thyroid autoimmunity, thyroid function, glucose metabolism and cardiovascular risk factors remains uncertain.Methods: We recorded thyroid function tests, BMI, IR markers comprising the Homeostasis Model Assessment for insulin resistance (HOMA-IR and HOMA-B), the Quantitative Insulin Sensitivity Check Index (QUICKI), HISI (Hepatic Insulin Sens...

BackgroundNon-dipping of nocturnal blood pressure is common among people with type 2 diabetes (T2D) and hypertension. Although the mechanism underlying the blunted nighttime response is unclear, insulin resistance is thought to play a role.AimsThis study aims to identify the pattern of nocturnal dipping of blood pressure in patients with T2D from a Portuguese population and its association with micro...

IntroductionNon-classical congenital adrenal hyperplasia (NC-CAH) is a chronic disease characterized by excessive androgen production. Affected children may have their quality of life negatively affected by the awareness of a medical condition, symptoms of hyperandrogenism and the burden of daily medication administration. Pediatric Quality of Life Inventory 4.0 (PedsQL) is a validated tool to assess health-related QoL (HRQoL).Meth...

IntroductionDiabetes mellitus (DM) due to cirrhosis is described as hepatogenous diabetes (HD). Despite being frequently described in the literature, it is not recognized as an entity by the ADA/EASD.Case reportWoman, 70 years old, previous history of autoimmune hepatitis with Child-Turcotte-Pugh A cirrhosis (CTP-A) since 2018, arterial hypertension and overweight (BMI 29.1 kg/m2). No personal or f...

IntroductionObesity is a chronic disease that is associated with several comorbidities, decreased quality of life, and increased mortality rate. Bariatric surgery is the most effective therapy for obese patients with class III and class II with metabolic diseases. Its effectiveness is not only related to the weight reduction, but also to the improvement of the metabolic profile. The aim of this study is to characterize the effects of gastroplasty with Ro...

Introduction: Obesity is a chronic disease whose association with increased cardiovascular morbidity and mortality, including heart failure, is well established. Not only is obesity intricately connected with an increased prevalence of concurrent risk factors, such as coronary artery disease, hypertension, diabetes mellitus, and obstructive sleep apnea, but it also exerts a direct impact on myocardial structure and pump performance. Over time, prolonged obesity fosters cardiac...